aav shctrl (Addgene inc)
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Addgene inc
aav shctrl
Aav Shctrl, supplied by Addgene inc, used in various techniques. Bioz Stars score: 95/100, based on 106 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aav-shctrl/PX552+(Plasmid+%2360958)/pmc12339988-44-3-4
Average 95 stars, based on 106 article reviews
Aav Shctrl, supplied by Addgene inc, used in various techniques. Bioz Stars score: 95/100, based on 106 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aav-shctrl/PX552+(Plasmid+%2360958)/pmc12339988-44-3-4
Average 95 stars, based on 106 article reviews
aav shctrl - by Bioz Stars,
2026-11
95/100 stars
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other:Article Title: GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration. Article Snippet: Article GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration Highlights • Diverse pathological stimuli upregulate GADD45G in astrocytes • Astrocytic GADD45G drives neuropathology via autonomous and nonautonomous actions • GADD45G interacts with MAP3K4 to activate neuroimmune signaling in astrocytes • GADD45G inhibition mitigates pathology and behavior deficits in an AD mouse model Authors Tianjin Shen, Wenjiao Tai, Dongfang Jiang, Shuaipeng Ma, Xiaoling Zhong, Yuhua Zou, Chun-Li Zhang Correspondence chun-li.zhang@utsouthwestern.edu In brief Shen et al. identify GADD45G as an astrocytic sensor of diverse pathological stimuli and show that it drives reactive gliosis, neuroinflammation, and synapse loss through cell-autonomous and -nonautonomous mechanisms.. Conversely, GADD45G inhibition mitigates histological and behavioral pathology in an Alzheimer’s disease model, highlighting it as a potential therapeutic target.. Shen et al., 2025, Neuron 113, 2176–2195 July 9, 2025 © 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. https://doi.org/10.1016/j.neuron.2025.04.033 ll Virus:Article Title: Sex-specific lymphatic responses to estrogen shape atherosclerosis in high-risk mice Article Snippet: .. Ten-week-old female C57BL/6 WT mice received 250 μL IP injections of 1 × 10 11 of adeno-associated virus type 1 (AAV1) encoding either a short hairpin RNA (shRNA) against Esr1 (shEsr1) or a shRNA:Article Title: Sex-specific lymphatic responses to estrogen shape atherosclerosis in high-risk mice Article Snippet: .. Ten-week-old female C57BL/6 WT mice received 250 μL IP injections of 1 × 10 11 of adeno-associated virus type 1 (AAV1) encoding either a short hairpin RNA (shRNA) against Esr1 (shEsr1) or a Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, Control:Article Title: Sex-specific lymphatic responses to estrogen shape atherosclerosis in high-risk mice Article Snippet: .. Ten-week-old female C57BL/6 WT mice received 250 μL IP injections of 1 × 10 11 of adeno-associated virus type 1 (AAV1) encoding either a short hairpin RNA (shRNA) against Esr1 (shEsr1) or a Knockdown:Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, Bioprocessing:Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, Expressing:Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, Construct:Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, Sequencing:Article Title: MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axis Article Snippet: Specifically, HEK293T cells (ATCC) were transfected with the AAV-CMV, AAV8 (Addgene; Cat No.112864), and AAV-helper (Addgene; Cat No.81070) plasmids in 150-mm dishes at 80% confluence. .. For Mcm7 knockdown, |